Predictive Analytics in Chronic Disease Management Using AI to Enhance Cardiovascular Health and Patient Record Outcomes
DOI:
https://doi.org/10.62497/irjai.117Keywords:
Predictive analytics, artificial intelligence, AI, disease management, clinical decision support, healthcare outcomesAbstract
Introduction: The integration of AI and predictive analytics into clinical workflows is transforming chronic disease management by enabling early risk detection, personalized treatment, and better resource use, especially in cardiovascular care. This study evaluated the clinical impact, predictive accuracy, and practical feasibility of AI-driven analytics for improving cardiovascular outcomes and optimizing patient records in a tertiary care setting.
Methodology: A prospective cohort study was conducted at KUST, Kohat, and PIMS, Islamabad, from January to December 2023, enrolling 290 adults with cardiovascular disease. Data from electronic health records and structured interviews informed supervised machine learning models (logistic regression and random forest), validated via cross-validation. Deployed as a real-time Streamlit app, the models were compared to the Framingham Risk Score. Primary outcomes were cardiovascular event prediction, with secondary analyses on treatment recommendations, patient satisfaction, and healthcare utilization pre- and post-AI implementation.
Results: The mean patient age was 58.4 years (SD ± 10.2), with a male predominance (54.48%). Common comorbidities included hypertension (70.34%), hyperlipidemia (42.76%), and diabetes (36.90%). The random forest model outperformed traditional risk scoring, achieving 81.57% accuracy, 85.31% sensitivity, and 78.96% specificity. Implementation of the AI-driven platform led to a reduction in cardiovascular events, including myocardial infarctions (from 28 to 19 cases) and strokes (from 18 to 9 cases). Post-AI, significant improvements were observed in lifestyle modifications (+13.11%), intervention referrals (+24.44%), and surgical procedures (+33.33%). Additionally, hospital admissions and emergency visits declined by 12.5% and 26.88%, respectively. Patient satisfaction was notably high, with 85.17% reporting ease of use and 80.69% expressing trust in AI-guided recommendations.
Conclusion: The deployment of AI-powered predictive analytics in cardiovascular care demonstrated significant improvements in risk prediction accuracy, patient outcomes, and healthcare delivery efficiency. These findings support the integration of AI as a viable, patient-centered tool in chronic disease management, offering a path toward more proactive, precise, and data-driven clinical interventions.
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Alowais SA, Alghamdi SS, Alsuhebany N, Alqahtani T, Alshaya AI, Almohareb SN, Aldairem A, Alrashed M, Bin Saleh K, Badreldin HA, Al Yami MS. Revolutionizing healthcare: the role of artificial intelligence in clinical practice. BMC medical education. 2023 ;23(1):689. https://doi.org/10.1186/s12909-023-04698-z.
Shiwlani A, Khan M, Sherani AM, Qayyum MU, Hussain HK. Revolutionizing Healthcare: The Impact Of Artificial Intelligence On Patient Care, Diagnosis, And Treatment. JURIHUM: Jurnal Inovasi dan Humaniora. 2024;1(5):779-90. http://jurnalmahasiswa.com/index.php/Jurihum/article/view/845/553.
Piette JD, List J, Rana GK, Townsend W, Striplin D, Heisler M. Mobile health devices as tools for worldwide cardiovascular risk reduction and disease management. Circulation. 2015 ;132(21):2012-27. https://doi.org/10.1161/CIRCULATIONAHA.114.008723.
Vaduganathan M, Mensah GA, Turco JV, Fuster V, Roth GA. The global burden of cardiovascular diseases and risk: a compass for future health. Journal of the American College of Cardiology 2022 ;80(25):2361-71. https://www.jacc.org/doi/epdf/10.1016/j.jacc.2022.11.005.
Rehman A, Naz S, Razzak I. Leveraging big data analytics in healthcare enhancement: trends, challenges and opportunities. Multimedia Systems. 2022 ;28(4):1339-71.
https://doi.org/10.1007/s00530-020-00736-8.
Khan MS, Arshad MS, Greene SJ, Van Spall HG, Pandey A, Vemulapalli S, Perakslis E, Butler J. Artificial intelligence and heart failure: A state‐of‐the‐art review. European Journal of Heart Failure. 2023 ;25(9):1507-25. https://doi.org/10.1002/ejhf.2994.
Mohsin SN, Gapizov A, Ekhator C, Ain NU, Ahmad S, Khan M, Barker C, Hussain M, Malineni J, Ramadhan A, Nagaraj RH. The role of artificial intelligence in prediction, risk stratification, and personalized treatment planning for congenital heart diseases. Cureus. 2023;15(8). DOI: 10.7759/cureus.44374.
Battineni G, Sagaro GG, Chinatalapudi N, Amenta F. Applications of machine learning predictive models in the chronic disease diagnosis. Journal of personalized medicine. 2020;10(2):21. https://doi.org/10.3390/jpm10020021.
Barrett M, Boyne J, Brandts J, Brunner-La Rocca HP, De Maesschalck L, De Wit K, Dixon L, Eurlings C, Fitzsimons D, Golubnitschaja O, Hageman A. Artificial intelligence supported patient self-care in chronic heart failure: a paradigm shift from reactive to predictive, preventive and personalised care. Epma Journal. 2019; 10:445-64. https://doi.org/10.1007/s13167-019-00188-9.
Pinsky MR, Dubrawski A, Clermont G. Intelligent clinical decision support. Sensors. 2022 ;22(4):1408. https://doi.org/10.3390/s22041408.
Amann J, Blasimme A, Vayena E, Frey D, Madai VI, Precise4Q Consortium. Explainability for artificial intelligence in healthcare: a multidisciplinary perspective. BMC medical informatics and decision making. 2020;20:1-9. https://doi.org/10.1186/s12911-020-01332-6.
Siontis KC, Noseworthy PA, Attia ZI, Friedman PA. Artificial intelligence-enhanced electrocardiography in cardiovascular disease management. Nature Reviews Cardiology. 2021 ;18(7):465-78. https://doi.org/10.1038/s41569-020-00503-2.
Bhavnani SP, Parakh K, Atreja A, Druz R, Graham GN, Hayek SS, Krumholz HM, Maddox TM, Majmudar MD, Rumsfeld JS, Shah BR. 2017 Roadmap for innovation—ACC health policy statement on healthcare transformation in the era of digital health, big data, and precision health: a report of the American College of Cardiology Task Force on Health Policy Statements and Systems of Care. Journal of the American College of Cardiology.2017;70(21):2696-718. https://www.jacc.org/doi/epdf/10.1016/j.jacc.2017.10.018.
Ranjan R, Ch B. A Comprehensive Roadmap for Transforming Healthcare from Hospital-Centric to Patient-Centric through Healthcare Internet of Things (IoT). Engineered Science 2024. DOI: 10.30919/es1175.
Ferrari R, Abergel H, Ford I, Fox KM, Greenlaw N, Steg PG, Hu D, Tendera M, Tardif JC, CLARIFY investigators. Gender-and age-related differences in clinical presentation and management of outpatients with stable coronary artery disease. International journal of cardiology. 2013 ;167(6):2938-43. https://doi.org/10.1016/j.ijcard.2012.08.013.
McAloon CJ, Osman F, Glennon P, Lim PB, Hayat SA. Global epidemiology and incidence of cardiovascular disease. InCardiovascular Diseases 2016 (pp. 57-96). Academic Press. https://doi.org/10.1016/B978-0-12-803312-8.00004-5.
Bragg F, Halsey J, Guo Y, Zhang H, Yang L, Sun X, Pei P, Chen Y, Du H, Yu C, Clarke R. Blood pressure and cardiovascular diseases in Chinese adults with type 2 diabetes: a prospective cohort study. The Lancet Regional Health–Western Pacific. 2021 1;7. DOI:https://doi.org/10.1016/j.lanwpc.2020.100085.
Andrade J, Khairy P, Dobrev D, Nattel S. The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circulation research. 2014 ;114(9):1453-68. https://doi.org/10.1161/CIRCRESAHA.114.303211.
George J, Devi P, Kamath DY, Anthony N, Kunnoor NS, Sanil SS. Patterns and determinants of cardiovascular drug utilization in coronary care unit patients of a tertiary care hospital. Journal of cardiovascular disease research. 2013;4(4):214-21. https://doi.org/10.1016/j.jcdr.2013.12.001.
Faizal AS, Thevarajah TM, Khor SM, Chang SW. A review of risk prediction models in cardiovascular disease: conventional approach vs. artificial intelligent approach. Computer methods and programs in biomedicine. 2021;207:106190. https://doi.org/10.1016/j.cmpb.2021.106190.
Patel SJ, Yousuf S, Padala JV, Reddy S, Saraf P, Nooh A, Gutierrez LM, Abdirahman AH, Tanveer R, Rai M. Advancements in Artificial Intelligence for Precision Diagnosis and Treatment of Myocardial Infarction: A Comprehensive Review of Clinical Trials and Randomized Controlled Trials. Cureus. 2024;16(5). DOI: 10.7759/cureus.60119.
Sabbatini AK, Nallamothu BK, Kocher KE. Reducing variation in hospital admissions from the emergency department for low-mortality conditions may produce savings. Health affairs. 2014;33(9):1655-63. https://doi.org/10.1377/hlthaff.2013.1318.

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Copyright (c) 2025 Dr. Haris Khan, Dr. Azaz Alam, Dr. Hesna Bouid, Dr. Hina Kamawal, Muhammad Hozaifa (Author)

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