Echocardiographic Assessment of Diastolic Dysfunction in Patients with Poorly Controlled Hypertension
DOI:
https://doi.org/10.62497//irjcs.107Keywords:
Diastolic Dysfunction, Hypertension, Echocardiography, Left Ventricular Function, Cardiovascular RiskAbstract
Introduction: Diastolic dysfunction is a common cardiac complication in patients with poorly controlled hypertension, contributing to increased morbidity and mortality. Early detection using echocardiography is crucial for effective management and the prevention of heart failure.
Materials and Methods: A cross-sectional study was conducted at the Department of Cardiology, Khyber Teaching Hospital (KTH), Peshawar, from January to December 2023. A total of 118 patients with poorly controlled hypertension were enrolled. Detailed clinical and demographic data were collected, and all participants underwent standardized echocardiographic assessment to evaluate diastolic function. Statistical analyses included chi-square tests, ANOVA, and multivariate logistic regression.
Results: Diastolic dysfunction was identified in 88 patients (74.6%). Grade I dysfunction was most common, observed in 37 patients (31.4%), followed by Grade II in 31 patients (26.3%), and Grade III in 20 patients (16.9%). Significant predictors of diastolic dysfunction included increasing age (OR 1.04, p = 0.008), longer hypertension duration (OR 1.10, p = 0.002), presence of diabetes mellitus (54 patients; 45.8%, OR 2.25, p = 0.023), dyslipidemia (62 patients; 52.5%, OR 1.75, p = 0.031), and elevated systolic blood pressure (OR 1.06, p = 0.015).
Conclusion: Diastolic dysfunction is highly prevalent among patients with poorly controlled hypertension and is associated with several clinical risk factors. Routine echocardiographic evaluation should be considered for early identification and optimal management.
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Copyright (c) 2025 Dr. Muhammad Aftab Anwar, Dr. Farkhanda Jabeen, Dr. Yahya Aman, Dr. Muhammad Umair, Dr. Wagma Shahriyar Khan (Author)
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